Scientist II, Bioinformatics

Website Astellas

The Astellas Institute of Regenerative Medicine (AIRM) is a wholly-owned subsidiary of Astellas Pharma and focused on the development and commercialization of stem cell and regenerative medicine therapies. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people’s heath around the world through the provision of innovative and reliable pharmaceutical products.

Developing innovative therapies is one of the most challenging, most essential and personally rewarding fields in science. This is the most exciting time to be a part of Astellas, a company with a uniquely collaborative and patient-focused culture. There’s something special about working at Astellas. It’s reflected in our focus on the people we serve, the way we treat each other and the results we achieve together as a company.

AIRM has a world-class R&D team, and is pursuing a diverse range of disease indications, ranging from macular degeneration (currently in clinical trials) and other ocular indications to vascular and autoimmune disease. AIRM’s intellectual property portfolio includes pluripotent stem cell platforms — both embryonic and induced pluripotent stem cells as well as other cell based therapy research programs. AIRM is headquartered in Marlborough, Massachusetts.



We are seeking a highly motivated and talented bioinformatician to join our R&D team and contribute to development of stem cell based therapies spanning multiple therapeutic areas. The successful candidate will have a track record of success in a collaborative research environment with a strong scientific background in biology and analysis of next generation sequencing data.


Essential Job Responsibilities:

Apply computational algorithms, software tools and data mining techniques for bioinformatics analysis of NGS data
Refine existing analysis pipelines/tools and implement new strategies/resources for analysis and visualizations to address changing project needs
Provide support to non-computational R&D scientists seeking to independently use established bioinformatics resources
Interpret results, prepare presentations and reports for technical and non-technical audiences
Assist with infrastructure support for data collection, storage and analysis


PhD (3+ years) or MS (7+ years) with degree in in bioinformatics, computational biology, computer science or other relevant discipline. Title commensurate with experience.
Strong scientific background in biology and NGS
Hands-on experience with NGS data analysis with expertise in differential expression and single cell processing
Proficiency with a variety of programming languages for statistical computing and generation of graphics
Fluency in at least one scripting language (i.e.: Python, Perl, Groovy)
Excellent communication and interpersonal skills and ability to effectively collaborate with other teams
Excellent work planning, organization and record keeping is essential

Experience with AWS or other cloud vendors
Experience with ChIP-seq and small RNA Seq
Proficient in aseptic mammalian cell culture
Experience with nucleic acid/protein isolation, RT-PCR and other standard molecular biology techniques


Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled


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